There was an interesting study recently that showed coming off actually caused weight re-gain an order of magnitude worse than yo-yo dieting.
The media spun it as GLP-1’s being evil and pointless, quelle surprise, but really it hints towards obesity being more than just “fixing your relationship with food” and acknowledging that there is more we don’t understand about why some people are fatter than others despite similar lifestyles.
Going to be an interesting decade as more data is gathered on these, that’s for sure.
"This review found that cessation of WMM [weight management medication] is followed by rapid weight regain and reversal of beneficial effects on cardiometabolic markers. Regain after WMM was faster than after BWMP [behavioral weight management programs]. These findings suggest caution in short term use of these drugs without a more comprehensive approach to weight management."
There are a couple recent stories that people put on weight something like 4x as fast if they go cold turkey after a GLP1 than if they quit a normal starvation diet. This intuitively makes sense, because an average GLP1 weight loss is way higher than most people can attain with willpower alone. So when they stop, the body screams "feeeeeeed me!" at incredible volume.
The media spun it as GLP-1’s being evil and pointless, quelle surprise, but really it hints towards obesity being more than just “fixing your relationship with food” and acknowledging that there is more we don’t understand about why some people are fatter than others despite similar lifestyles.
Going to be an interesting decade as more data is gathered on these, that’s for sure.