BG3 works well on my new recent install of Debian Bookworm with nonfree sw on, Nvidia RTX 2080 SUPER, nvidia prop driver 525 or 535 I think, KDE Plasma set to Xorg (Wayland caused some flickering, supposedly bad interaction between Wayland and nvidia drivers).

I think I don't have advanced stuff like DLSS and HDR though, maybe I could if I did some tinkering.