I find that effective dosage is the most surprising aspect of this study
>Interventions Study medications were psilocybin, 25 mg/70 kg, vs diphenhydramine, 50 mg (first session), and psilocybin, 25-40 mg/70 kg, vs diphenhydramine, 50-100 mg (second session). Psychotherapy included motivational enhancement therapy and cognitive behavioral therapy.
25mg is an extremely small dose! Much smaller than most micro-dose regiments at 0.5g
25mg is not a small dose if you're actually measuring the psilocybin rather than the dried weight of the mushroom fruit. The exact psilocybin weight ratio depends on the strain of mushroom, but typically dried P. Cubensis is about 1% psilocybin by weight. This means that 25mg of psilocybin roughly corresponds to 2.5g of dried shrooms.
>Interventions Study medications were psilocybin, 25 mg/70 kg, vs diphenhydramine, 50 mg (first session), and psilocybin, 25-40 mg/70 kg, vs diphenhydramine, 50-100 mg (second session). Psychotherapy included motivational enhancement therapy and cognitive behavioral therapy.
25mg is an extremely small dose! Much smaller than most micro-dose regiments at 0.5g