They're meant to be dual duty. There aren't any road car engines I'm aware of that use individual throttle bodies or 12+ compression without direct injection.
The S54 engine which came before the S65/85, was also high revving, had 11.5:1 compression ratio and didn't have any of the rod bearing issues. The 20v Toyota 4AGE also had them too with a high compression ratio.
The S54 absolutely had rod bearing issues. There was a recall on the 2001-2003.5 M3s to replace them and BMW switched to 60w oil as part of the remediation. They’re still having issues to this day.
The S54 is also notorious for VANOS issues and cam drive failures. I had to replace the solenoid pack on mine but elected to not upgrade the drive while I was in there.