Used to use MacPorts for many, many years. But grew tired of it breaking important packages or just failing to update when doing macOS major version updates.

Also, MacPorts can many times just fail to install a package or fail to update a series of dependencies. Good luck then getting your operation important packages running ..

Anyway, switched to Brew completely a while ago when updating to Big Sur, so have no idea if Brew will also do the same thing over time, but at least their system seems more simple, which might result in less breakage.

I've given it a whirl, and while it's better than Brew, that's not a high bar to pass. Macports suffers from the same lack of software and strange idiosyncrasies that crop up in Brew, and it really doesn't justify it's place in my workflow.